A new preprint at BioRxiv: Post-embryonic maturation of the C. elegans motor circuit. (PDF)
HIGHLIGHTS:
– Post-embryonic motor circuit maturation was reconstructed by synapse-resolution serial EM
– Motor patterns are maintained as the circuit matures from asymmetric to symmetric configuration
– Programmed rewiring gradually and sequentially transforms the circuit structure
– Preparatory and communicative wiring-rewiring allows maturation without functional disruption.