Welcome to the Zhen Lab
C. elegans is a compact model to study fundamental principles that govern circuit assembly and functions. We combine electron microscopy, genetics, optogenetics, calcium imaging, and electrophysiology to address how its nervous system develops and operates. We apply tools and insights obtained from our C. elegans and mouse studies to reveal circuit deficits that underlie human neurological disorders.
C. elegans wiring
Preprints & Recent Publications
Towards a live soft microrobot: optogenetic locomotion control of Caenorhabditis elegans Accepted, Science Robotics, available July 2021