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Welcome to the Zhen Lab

C. elegans is a compact model to study fundamental principles that govern circuit assembly and functions.‚Äč We combine computational biology, electron microscopy, genetics, optogenetics, calcium imaging, and electrophysiology to address how its nervous system develops and operates. Insights obtained from our C. elegans and mouse studies to reveal circuit deficits that underlie human neurological disorders.

Resources

C. elegans wiring

nemanode.org

*NEW* 3D models of
C. elegans neurons

https://zenodo.org/record/5637219
https://zenodo.org/record/5525883

Codes (nemanodes)

https://github.com/dwitvliet/NemaNode

Original EM images

https://bossdb.org/project/witvliet2020

Plasmids

https://www.addgene.org/Mei_Zhen/

Other codes

https://github.com/zhenlab-ltri

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