Skip to content


Welcome to the Zhen Lab

C. elegans is a compact model to study fundamental principles that govern circuit assembly and functions.​ We combine computational biology, electron microscopy, genetics, optogenetics, calcium imaging, and electrophysiology to address how its nervous system develops and operates. Insights obtained from our C. elegans and mouse studies to reveal circuit deficits that underlie human neurological disorders.


C. elegans wiring

*NEW* 3D models of
C. elegans neurons

Codes (nemanodes)

Original EM images


Other codes

Follow us on Twitter